Oncology Abstracts

Page 1 of about 2 results

Single cell transcriptome analysis reveals human prostate cancer cells upregulate retinoic acid signalling in response to androgen withdrawal

Clark Ashlee K , Nim Hieu , Lister Natalie , Lawrence Mitchell G , Keerthikumar Shivakumar , Goode David L , MURAL , Wang Hong , Papargiris Melissa , Ryan Andrew , Azad Arun , Frydenberg Mark , Risbridger Gail P , Taylor Renea A

A current challenge in cancer therapeutics is incomplete response to treatment and emergence of therapy-resistant disease. Androgen deprivation therapy (ADT), the standard treatment for advanced prostate cancer, and effectively reduces the tumour burden in most patients. Yet, residual tumour cells that withstand ADT eventually develop lethal castration-resistance. Eliminating these castrate-tolerant cells, by combining ADT with other treatments, might delay or even prevent cas...

0 shares

oa0001p042 | (1) | PacRim7

PARP inhibitor and CX-5461 combination therapy as a novel treatment strategy for castrate-resistant prostate cancer

Porter Laura H , Lawrence Mitchell G , Choo Nicholas K , Sandhu Shahneen , Wang Hong , Melbourne Urological Research Alliance (MURAL) , Pook David , Sanij Elaine , Pearson Richard B , Hannan Ross , Furic Luc , Taylor Renea A , Risbridger Gail P

Abstract unavailable....

0 shares

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more

Oncology Abstracts

Single cell transcriptome analysis reveals human prostate cancer cells upregulate retinoic acid signalling in response to androgen withdrawal

PARP inhibitor and CX-5461 combination therapy as a novel treatment strategy for castrate-resistant prostate cancer

BiosciAbstracts