Searchable abstracts of presentations at key conferences in oncology

oa0001p025 | (1) | PacRim7

Estrogen receptor regulated miR-342 suppresses a pro-metastatic gene network

Lumb Rachael , Arnet Victoria K , Johnstone Cameron N , Pillman Katherine A , Toubia John , Hackett-Jones Emily , Phillips Caroline A , Pinweha Pannapa , Roslan Suraya , Li Xiaochun , Beilharz Traude , Khew-Goodall Yeesim , Goodall Gregory J , Anderson Robin L , Gregory Philip A

Breast cancer is the most frequently diagnosed cancer in women and the second leading cause of female cancer related death. Despite significant advances in early detection, surgery and therapy, treatment remains a challenge if metastatic disease develops. Metastasis occurs with high frequency in triple negative (ER/PR/HER2 negative, TNBC) breast cancers, which are a heterogeneous group of cancers with poor clinical outcome. We used an integrated approach to identify miRNAs tha...