Searchable abstracts of presentations at key conferences in oncology

oa0001p020 | (1) | PacRim7

Circular RNAs add further diversity to AR isoform repertoire

Cao Subing , Ma Tianfang , Ungerleider Nathan , Roberts Claire , Jin Lianjin , Concha Monica , Wang Xia , Baddoo Melody , Fazli Ladan , Corey Eva , Sartor Oliver , Dong Xuesen , Flemington Erik , Dong Yan

Circular RNAs (circRNAs) are a newly appreciated class of regulatory RNA species that play vital roles in various cell signaling and metabolic processes. Deregulated expression of circRNAs has been found to be associated with various human diseases including many types of cancer. Despite their growing links to cancer, there has been limited characterization of circRNAs in metastatic castration-resistant prostate cancer, the major cause of prostate cancer mortality. Here, initi...