Searchable abstracts of presentations at key conferences in oncology

oa0001p018 | (1) | PacRim7

Assessing alterations in organelle contacts during prostate cancer development

Evergren Emma , Butler Lisa

Aggressive prostate cancer is characterized by altered lipid metabolism and metabolic stress. At a subcellular level these changes are localized to the endoplasmic reticulum (ER) and mitochondria. Traditionally the function of these organelles has been studied separately. A growing body of evidence shows that the interaction between mitochondria and ER at specialized membrane contact sites play a key role in regulating fundamental cellular processes such as lipid synthesis, mi...