Searchable abstracts of presentations at key conferences in oncology

oa0001p039 | (1) | PacRim7

Quest for the lost andromedin

Ong Christopher , Gleave Martin

The exquisite dependency of PCa on androgens for growth and survival was first recognized in the 1940’s when Huggins and Hodges demonstrated the antitumour activity of hormonal manipulation in the treatment of PCa. Since then, androgen deprivation therapy has been the standard of care in the treatment of metastatic and locally advanced PCa. Drugs targeting the androgen/androgen receptor (AR) axis have been well-validated clinically and remain without a doubt the most effe...