Searchable abstracts of presentations at key conferences in oncology

oa0001p041 | (1) | PacRim7

Extending genetic portraits of human prostate cancer

Pestell Richard

This study was conducted to define the role of Dachshund in prostate cancer, through assessing human prostate cancer samples and through genetic deletion in the mouse. Prostate cancer (PCa), the second leading cause of death in American men. A better molecular understanding of the disease is necessary in order to develop novel targeted therapies of metastatic PCa. Known genetic drivers to tumor initiation include PTEN and NKX3.1 deletions, rearrangements of the TMPRSS2</em...